Peter Ambros, PhD
Peter Ambros, PhD, Associate Professor at the Children's Cancer Research Institute (CCRI) in Vienna, Austria discusses the way in which arrays are helping to unravel the complexities of the cancer genome and guiding patient-tailored treatment strategies.
There is an emerging recognition that an improved ability to assess the cancer genome will help clinicians better stratify patients for diagnosis, prognosis, and therapy selection. This includes an evolving appreciation for the wealth of emerging clinically actionable variants that should be validated and included alongside accepted diagnostic markers to improve cancer diagnosis and disease staging.
The work at the CCRI is helping to advance diagnosis, prognosis, and treatment strategies for children and adolescents suffering from cancer. To achieve this aim, the work of Dr. Ambros's group is primarily devoted to understanding the genomic and cell biological aspects of neuroblastomas and other pediatric solid tumors such as nephroblastomas, rhabdomyosarcomas, and rhabdoid tumors. Genomic features of pediatric tumors can frequently help in the diagnostic workup and, importantly, can offer additional prognostic information. They aim to apply the most innovative and robust genomic diagnostic tools and provide this information to the treating oncologist to choose the most suitable treatment options available to young patients.
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